Alternate pathways to mastery of material

Material Mastery: Situating Digital Library Use in University Research Practices

In the past several years, researchers in library and information science, computer science and management information systems have claimed that knowledge workers will transform important characteristics of work due to increased access to digital libraries over the Internet. To explore the in ̄uence of digital libraries on knowledge work, this study investigated the use of paper and electronic m...

Molecular Pathways Adaptive changes result in activation of alternate signaling pathways and acquisition of resistance to aromatase inhibitors

Hormone therapy is an effective approach for the treatment of breast cancer. Although the antiestrogen tamoxifen has had amajor impact on the treatment of the disease, aromatase inhibitors (AIs), which reduce estrogen synthesis, have recently proved to bemore effective. These agents are now used as first-line therapy for postmenopausal breast cancer. Nevertheless, despite the efficacy of these ...

Adaptive changes result in activation of alternate signaling pathways and acquisition of resistance to aromatase inhibitors.

Hormone therapy is an effective approach for the treatment of breast cancer. Although the antiestrogen tamoxifen has had a major impact on the treatment of the disease, aromatase inhibitors (AIs), which reduce estrogen synthesis, have recently proved to be more effective. These agents are now used as first-line therapy for postmenopausal breast cancer. Nevertheless, despite the efficacy of thes...

Alternate pathways of glycolate synthesis in tobacco and maize leaves in relation to rates of photorespiration.

After a preliminary period in light, leaf disks floated on 10 mm alpha-hydroxy-2-pyridinemethanesulfonic acid to inhibit glycolate oxidase accumulate glycolate at average initial rates of 67 micromoles in tobacco and 8 micromoles per gram fresh weight per hour in maize under optimal conditions in air. In the presence of (14)CO(2), the glycolate synthesized has a high specific radioactivity in i...

Microwave–Material Interactions and Dielectric Properties, Key Ingredients for Mastery of Chemical Microwave Processes